Description
Benturex 30mg (clobenzorex) is used to reduce body weight in obese or overweight patients. Often it is prescribed in a regimen of weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity for obese or overweight patients with the presence of other risk factors.
Clobenzorex Mechanism of Action
Sympathomimetic amine that acts on the ventrolateral nucleus of the hypothalamus, increasing the release of norepinephrine and dopamine in the synaptic spaces and decreasing their reuptake in the presynaptic nerve endings, which is why there is an increase in the concentrations of adrenaline and dopamine. Norepinephrine curbs appetite by activating alpha 4 and beta 1 receptors in the hypothalamic nuclei.
Therapeutic indications Clobenzorex
Treatment of patients who are overweight or obese, with some associated pathology and who have not responded to diet and physical activity.
Adverse Reactions Clobenzorex
pulmonary hypertension; drug tolerance, dependence and withdrawal syndrome; psychotic reactions or psychosis, depression, nervousness, agitation, sleep disturbances and vertigo; tachycardia, palpitations, arterial hypertension and precordial pain; dry mouth and constipation; dysuria and urinary retention
